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Brands

Banamine, Finadyne

Availability

Injectable: 50 mg/mL in 50 mL & 100 mL vials

Oral Granules: 250 mg in 10 gm sachets

Pharmacology

Flunixin meglumine is a nonsteroidal anti-inflammatory drug. It is a highly substituted derivative of nicotinic acid, and when compared with other NSAIDs it is structurally unique. It is an inhibitor of cyclooxygenase. It, like other NSAIDs, exhibits anti-inflammatory, antipyretic, and analgesic effects.

This drug is rapidly absorbed after oral administration. It is not clear how this drug is distributed in the body or metabolized, although some of the drug appears to be excreted in small amounts in the urine.

Use cautiously in pregnant animals, and those animals with renal, hepatic or hematologic diseases.

Indications

Uses include before and after ophthalmic and general surgery, disk and associated problems of lameness, and arthritis.

Drug Interactions or Contraindications

Interactions similar to all NSAIDs. Avoid concomitant use with phenytoin, valproic acid, oral anticoagulants, other anti-inflammatory agents, steroids, salicylates, and sulfonamides.

May reduce effects of furosemide when used together.

Adverse Reactions

CNS:  stimulation, ataxia, hyperventilation, muscle weakness (all may be transient symptoms).

GI:  diarrhea, GI ulceration.

Dosage Recommendations

2.5 mg/kg , SQ or IM , q12hrs. ⁶

or

2.5 mg/kg , SQ , q12hrs - q24hrs.  ¹

Considerations

• Not recommended to mix injectable in with other drugs.
• Store at 2-30^o C.

Posted on June 23, 2003, 16:26, Last updated on December 14, 2008, 11:58 | NSAIDS