Chase has not been neutered, and shows normally developed testicles. However, he has never showed any sexual maturity around unspayed females. The siblings with moderate and mild hydrocephaly have showed some sexual maturity and have displayed interest in the unspayed females, but have lacked the ability to impregnate any of the females. The question that arises, is, are they able to reproduce?
After the seizure Chase was hypersensitive to touch for one minute, and after 2 minutes his posture appeared normal, although somewhat lethargic. He was rushed to the vet immediately where he was given 2.5mg/kg of Valium to stop further seizure activity. The medication kept him sedated for several hours.
We started Chase on phenobarbital 0.2ml BID (twice a day), based on 2mg/kg.
Chase had one seizure at 11pm. The vet was called the next morning and and the dosage increased to 2.2 mg/kg BID (twice a day).
April 12, at 5:45 pm
Yet another seizure was witnessed. The vet was called the next day where he recommended the dosage again be increased to 2.4 mg/kg BID.
April 25, at 9:30pm
Chase had another seizure, and a call was placed to the vet the next morning. The vet stated that at this time he didn’t want to increase the dosage of phenobarbital unless additional seizures were witnessed.
May 6, at 5:30pm
There were 3 successive seizures, and a call was placed to the vet. Based on the additional seizure activity he said to increase the dose of phenobarbital to 2.6 mg/kg BID, but indicated he was concerned about Chase’s heart and requested he be brought in for a check up. We scheduled the appointment for May 11. On exam of Chase the vet said his heart was fine, and recommended we increase the dosage of phenobarbital to 2.8 mg/kg BID.
May 20, at 7pm
There were 3 successive seizures. I called the vet and was told to again increase the dosage to 3.5 mg/kg BID. The vet stated that if the seizure activity continued to give him an extra 0.5 mg.
June 2nd, at 8pm
There was one seizure. An extra 0.5 mg was given with Chase’s evening dose, so that he received 4.0 mg/kg. The following day on June 3, at 8am, there was another seizure, and again he was given the 4.0 mg/kg for his morning dose.
Thereafter I resumed his 3.5 mg/kg dosage until on July 8, at 7pm, he had two successive seizures. At this point I noticed the seizures looked like they were taking a physical toll on Chase. It was decided at that point to increase his dose to 4 mg/kg which is the upper limit of what we determined was the therapeutic range of 2-4mg/kg BID of phenobarbital. After contacting the vet to let him know the dose Chase was now receiving, he said not to give him more than 4 mg/kg BID, after I explained that Chase was lethargic and drowsy most of the day on that dose.
Photo 1: Chase at 3 weeks of age.
Photo 2: Chase at 3 weeks along side of sibling.
Note size comparison of both body and head.
Photo 3: Chase at 1 month of age.
Photo 4: Chase at 6 weeks of age.
Photo 5: Sibling comparison at 14 weeks.
Photo 6: Chase at 9 months of age.
Case history and photos courtesy of Charlene M. Crain, MBA, BSMT (ASCP) and Dr. Greg Rich, DVM, at West Esplanade Veterinary Hospital
Posted on August 27, 2004, 13:56,
Last updated on April 9, 2010, 16:49