Figure 2: Hemangiosarcoma in adult male rat
Case history and photos

History

Male, 14-month-old, agouti dumbo rat. No history of illness.

Clinical Signs

Owner noticed swelling on the back/side of the neck and extreme lethargy early in the morning. As the day progressed the swelling increased rapidly and he showed loss of motor control. The cervical mass felt hard and attached. The rat was taken to the vet in the late afternoon. His temperature was 95 degrees. He refused all food and fluids.

Diagnosis

A fine needle aspiration was performed at the veterinarian’s office and upon reading the slide cancerous type cells were seen. The rat was initially diagnosed with an unknown cancerous cervical mass.

Treatment

The rat was given oxygen and put on a heating pad to raise body temperature. He received an injection of baytril. Rat died at the veterinarian’s office.

Necropsy and Final Diagnosis

A necropsy was performed on the rat and showed a large maroon cervical mass as well as maroon spotting on the lungs. The tumor, once removed and dissected, revealed a lumpy, dark red, gelatin like interior. The tumor and the lung tissue were put in formalin and sent out for pathology.

The findings showed that both the mass and the spotting on the lungs were hemangiosarcoma, an aggressive malignant cancer that originates in the cells that line the blood vessels (endothelial cells).

Discussion

Although it can theoretically occur anywhere blood vessels are present in the body hemangiosarcoma is most prevalent in the heart, on the skin (or under the skin), and in the spleen. Sarcoma, cancer of the soft tissue, is typically a highly malignant type of cancer. Even the skin forms tend to metastasize to other parts of the body.

Photos

Posted on February 1, 2006, 11:02, Last updated on March 5, 2010, 15:14 | Figures