Brand
Mitaban
Availability
As Amitraz 19.9% topical solution for dilution in 10.6 mL bottles.
Pharmacology
Amitraz is a diamide topical antiparasitic agent belonging to the class of monoamine oxidase inhibitors. It appears to effect the central nervous system of
those organisms that are susceptible. It also appears to have alpha-2 adrenergic ability.
This drug can cause significant increase in plasma glucose levels by inhibiting insulin release via alpha-2 adrenergic activity.
The safety of this drug has not been established in young animals or pregnant animals.
Indications
Used in treatment for demodectic mange, notoedres, and sarcoptid mites.
Drug Interactions or Contraindications
Do not mix with other antiparasiticides.
Do not use corticosteroids and other immunosuppressants in animals with demodicosis due to immunosuppressive effects.
Ivermectin recommended safer to use in pet rats.
Adverse Reactions
CNS: transient sedation
GI: may be toxic if swallowed
Dosage Recommendations
An established dose for use in rats is to dilute 5X the recommended amount for dogs and wash animal at 2 week intervals for 3 to 6 treatments (ie; 10.6 mL or 1 bottle in 10 gal. water. This method safer for rodents since surface to body ratio
is greater than dogs). Following the treatment keep the rat warm and free from drafts until dry.
Refer to AMITRAZ USE IN GERBILS, HAMSTERS AND RATS by Tynes, Valerie V. DVM.
Considerations
If treating around eyes, use opthalmic protectant with petrolatum before treating.
Refrain from use in pyoderma until lesions healed.
Amitraz is flammable until diluted in water. Wear gloves while treating animal, protect any exposed skin on hands and arms and wash thoroughly after treatment.
Avoid any vapors and flush unused portion down drain, and rinse any container used to mix with water and then dispose.
Posted on June 28, 2003, 07:01,
Last updated on June 6, 2008, 19:03
| Anti-Infectives
