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Antiandrogens are believed to have two modes of action:
1. inhibit pituitary gonadotrophin release and,
2. effecting a behavioral sex center.
Tardak’s effects are known to be reversible when the medication is stopped.
While not licensed for rats, the Pfizer drug company advised that it could be used at the same dose rate and indication as for male dogs and cats:- i.e. 0.1 mL subcutaneous for average 500g rat, and can be repeated 10 days after the first injection if not apparently working or as needed - possibly after 3 - 4 weeks if desired effect wears off. (Additional veterinarian reference of dose use:17)
VET SHOULD FOLLOW INSTRUCTIONS AS ON DATA SHEET. Main indications are for certain forms of aggressiveness and nervousness in male rats. (A form of chemical castration.)
NB Changes in coat color may occur so if this could be a problem e.g. in showing animals other areas of injection may need to be considered.
Posted on February 6, 2005, 16:56,
Last updated on December 24, 2008, 12:48