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Brand

Benylin-E
Humibid
Organidin NR
Robitussin

Pharmacology

Guaifenesin increases respiratory tract fluid by reducing adhesiveness and surface tension. This in turn helps to thin the mucus making it easier to cough up and remove from the airways.

Guaifenesin is conjugated in the liver and excreted into the urine. It is reported to cross placental barrier; however adverse effects in newborns have not been documented at this time.

Indications

Used for relief in bronchitis and respiratory infections where a dry, non productive, cough is present.

Drug Interactions or Contraindications

Contraindicated in hypersensitivity.

Not recommended in coughs accompanied by excessive secretions.

Adverse Reactions

CNS: drowsiness, restlessness.

GI: poor appetite.

Dosage Recommendations

1/10th the child’s dose ( this dosage is empiric in rat’s ) ³

Considerations

Encouraging fluids, and fruit that is juicy, along with the use of a humidifier help to liquify secretions.

Store at room temperature.

Posted on June 28, 2003, 07:21, Last updated on June 6, 2008, 18:54 | Respiratory Drugs